Torben Plesner.

A complete of 13 of the 15 patients with a response in the cohort that received 16 mg per kilogram had data that may be evaluated, and these patients either had a decrease in the bone marrow plasma-cell level or had a level that remained steady below 5 percent . In individuals who had a response to treatment and received 16 mg per kilogram, the estimated median time to the 1st response was 0.9 months , and the estimated median time to the best response was 1.8 months . The approximated median duration of response was 6.9 months in the cohort that received 8 mg per kilogram and was not reached in the cohort that received 16 mg per kilogram, with 65 percent of the individuals who had a response in this cohort remaining progression-free at 12 weeks.The hospitals and treatment centers with the best overall rates of diabetes sufferers with blood pressure at or below the mark of 140/90 also had the best rates of overtreatment, they found. This is likely due to focusing on a target than on an individualized strategy – a phenomenon that could be tied to performance incentives and general public reporting practices currently in place, says Kerr, an associate of the U-M Institute for Healthcare Policy and Advancement and the Michigan Diabetes Training and Research Center.